TTBK1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TTBK1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,377 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TTBK1-associated genes across cancer lineages are RANGAP1, ZC3H7B, and SNPH. Each is linked with TTBK1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TTBK1-to-partner and partner-to-TTBK1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TTBK1 versus RANGAP1 in GBM, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TTBK1→partner) and Y-score (partner→TTBK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMRANGAP1 →+0.545+0.415<.001<.00132
CCRCCZC3H7B →+0.564+1.229.001.00132
GBMSNPH →+0.670+0.297<.001<.00132
GBMPCYT1B →+0.713+0.272<.001<.00132
GBMABHD17B →+0.502+0.405<.001<.00132
CCRCCCAP2 →+0.689+0.777.004.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,377 associations by consensus.

TTBK1 vs RANGAP1 — GBM

Per-sample scatter of TTBK1 vs RANGAP1 in GBM (Pearson r = 0.46).

Explore this scatter interactively →

Exploration