TSPOAP1

Across TCGA patient cohorts, TSPOAP1 protein abundance is significantly associated with the RNA expression of many other genes, with 5,416 significant associations in total. GBM shows the largest number of these associations.

The most reproducible TSPOAP1-associated genes across cancer lineages are PORCN, LRRC59, and PPP2R5D. Each is linked with TSPOAP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPOAP1-to-partner and partner-to-TSPOAP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSPOAP1 versus PORCN in LUAD, with a Pearson correlation of 0.83.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPOAP1→partner) and Y-score (partner→TSPOAP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	PORCN →	+1.342	+1.192	.006	<.001	3	1
LUAD	LRRC59 →	+0.546	+0.845	<.001	.001	3	1
LUAD	PPP2R5D →	+0.942	+1.182	.004	.008	3	1
LUAD	SMC4 →	+1.479	+0.838	<.001	.001	3	1
LUAD	AMOTL2 →	+1.622	+1.071	.002	.003	3	1
LUAD	CEP70 →	+1.556	+0.972	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,416 associations by consensus.

TSPOAP1 vs PORCN — LUAD

Explore this scatter interactively →