Q-omics provides the consensus-scored TSPAN9-IT1 profile across patient tissues and cancer cell-line models. TSPAN9-IT1 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in MESO. Among the 18 cancer types available for tumor–normal comparison, TSPAN9-IT1 is differentially expressed in 2, with the highest sampling consensus in BRCA. Additionally, TSPAN9-IT1 RNA expression shows 6,263 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight MESO, BRCA, and STAD as cancer lineages where TSPAN9-IT1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TSPAN9-IT1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TSPAN9-IT1 survival associations across molecular data types. TSPAN9-IT1 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TSPAN9-IT1 RNA expression–survival associations across cancer types. High TSPAN9-IT1 expression shows unfavorable associations in MESO, LUSC, LUAD, UVM, OV and COAD. The MESO Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .019). Together, the overview and detailed table identify MESO as the clearest survival context for TSPAN9-IT1 RNA expression.
This table summarizes TSPAN9-IT1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for TSPAN9-IT1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. TSPAN9-IT1 shows lower tumor expression in BRCA and higher tumor expression in KIRC. The BRCA box plot shows higher TSPAN9-IT1 RNA expression in normal versus tumor tissue (log2 FC = −0.061, t-test p < 0.001).
This table shows molecular features associated with TSPAN9-IT1 in patient tissues and cancer cell lines. In patient samples, TSPAN9-IT1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
