TSPAN32

Across TCGA cell cohorts, TSPAN32 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,356 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TSPAN32-associated GO terms across cancer lineages are Establishment of protein localization to plasma membrane, Regulation of ATF6-mediated unfolded protein response, and Glycine decarboxylation via glycine cleavage system. Each is linked with TSPAN32 in more than 8 cancer types. Because this analysis shows association rather than direction, both TSPAN32-to-partner and partner-to-TSPAN32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to plasma membrane grouped by TSPAN32-low versus TSPAN32-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN32→partner) and Y-score (partner→TSPAN32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Establishment of protein localization to plasma membrane →	+0.059	+0.354	.005	.001	3	9
BONE	Regulation of ATF6-mediated unfolded protein response →	+0.140	+0.434	<.001	.004	3	7
SOFT_TISSUE	Glycine decarboxylation via glycine cleavage system →	-0.149	-0.292	.005	.001	3	7
BONE	Substrate adhesion-dependent cell spreading →	+0.158	+0.534	.003	.006	3	7
BONE	Response to acid chemical →	+0.073	+0.549	.002	.002	3	7
BLOOD_Leukemia	Protein targeting to vacuole involved in autophagy →	+0.147	+2.354	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,356 associations by consensus.

Establishment of protein localization to plasma membrane by TSPAN32 expression — SOFT_TISSUE

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