TSPAN32

Across TCGA pan-cancer cohorts, TSPAN32 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of TSPAN32’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where TSPAN32 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TSPAN32 is over-expressed in tumor, although a few such as LUAD and BLCA show the opposite, repressed pattern.

KIRC, LUAD, and BLCA are the cancer types where TSPAN32 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TSPAN32 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	All	+0.701	<.001	11	view →
LUAD	Male	III,IV	−1.346	<.001	9	view →
BLCA	All	IV	−0.621	<.001	9	view →
LUSC	Male	II,III,IV	−1.440	<.001	8	view →
UCEC	All	II,III,IV	−1.051	<.001	6	view →
BRCA	All	II,III,IV	−0.249	<.001	6	view →
COAD	All	III,IV	−0.293	.044	3	view →
KICH	Female	All	−0.410	.003	2	view →
PRAD	All	All	−0.243	<.001	2	view →
CHOL	All	All	+0.474	.038	1	view →
ESCA	Female	All	−0.473	.010	1	view →
THCA	Male	IV	+0.270	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

TSPAN32–KIRC

Open the KIRC breakdown →