TSPAN32

Across TCGA cell cohorts, TSPAN32 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. CNS shows the largest number of these associations.

The most reproducible TSPAN32-associated genes across cancer lineages are SPATA31D1, OR8B4, and F11. Each is linked with TSPAN32 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSPAN32-to-partner and partner-to-TSPAN32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SPATA31D1 grouped by TSPAN32-low versus TSPAN32-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSPAN32→partner) and Y-score (partner→TSPAN32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	SPATA31D1 →	+0.006	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR8B4 →	+0.034	+4.887	<.001	.009	3	1
LARGE_INTESTINE	F11 →	+0.073	+4.467	<.001	.004	3	1
BLOOD_Leukemia	KRTAP5-6 →	+0.248	+3.874	<.001	.005	3	1
CNS	H1-8 →	+0.030	+6.357	<.001	<.001	3	1
CNS	OR8K3 →	+0.006	+5.754	.002	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

SPATA31D1 by TSPAN32 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →