TSKU

Across TCGA patient cohorts, TSKU protein abundance is significantly associated with the protein abundance of many other proteins, with 11,810 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TSKU-associated proteins across cancer lineages are UXS1, C8G, and GNPTG. Each is linked with TSKU in more than 5 cancer types. Because this analysis shows association rather than direction, both TSKU-to-partner and partner-to-TSKU results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSKU versus UXS1 in CCRCC, with a Pearson correlation of 0.59.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TSKU→partner) and Y-score (partner→TSKU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	UXS1 →	+0.360	+0.644	<.001	<.001	3	5
OV	C8G →	+0.942	+0.890	<.001	<.001	3	5
CCRCC	GNPTG →	+0.392	+0.623	.003	<.001	3	5
PDAC	STC1 →	+1.044	+0.880	<.001	<.001	3	5
GBM	HDAC1 →	-0.328	-0.692	.001	<.001	2	6
OV	VNN2 →	+1.145	+0.652	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,810 associations by consensus.

TSKU vs UXS1 — CCRCC

Explore this scatter interactively →