TSKU

Across TCGA cell cohorts, TSKU RNA expression is significantly associated with the go_rna of many other GO terms, with 4,291 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TSKU-associated GO terms across cancer lineages are Anterior commissure morphogenesis, Negative regulation of transforming growth factor beta1 production, and Regulation of myofibroblast differentiation. Each is linked with TSKU in more than 16 cancer types. Because this analysis shows association rather than direction, both TSKU-to-partner and partner-to-TSKU results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Anterior commissure morphogenesis grouped by TSKU-low versus TSKU-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSKU→partner) and Y-score (partner→TSKU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Anterior commissure morphogenesis →	+1.665	+2.466	<.001	<.001	3	17
BLOOD_Lymphoma	Negative regulation of transforming growth factor beta1 production →	+0.816	+1.612	.001	<.001	3	15
OVARY	Regulation of myofibroblast differentiation →	+0.166	+1.399	<.001	<.001	3	14
LUNG_NSCLC_LUSC	Negative regulation of myofibroblast differentiation →	+0.247	+2.172	<.001	<.001	3	14
KIDNEY	Negative regulation of transforming growth factor beta production →	+0.271	+1.533	<.001	<.001	3	13
KIDNEY	Nuclear receptor-mediated signaling pathway →	+0.071	+1.325	.002	.006	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,291 associations by consensus.

Anterior commissure morphogenesis by TSKU expression — BLOOD_Myeloma

Explore this box plot interactively →