TSHZ2

Across TCGA patient cohorts, TSHZ2 protein abundance is significantly associated with the RNA expression of many other genes, with 889 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible TSHZ2-associated genes across cancer lineages are RORA-AS2, MCM5, and GINS1. Each is linked with TSHZ2 in more than 1 cancer types. Because this analysis shows association rather than direction, both TSHZ2-to-partner and partner-to-TSHZ2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TSHZ2 versus RORA-AS2 in LSCC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TSHZ2→partner) and Y-score (partner→TSHZ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	RORA-AS2 →	+0.522	+0.751	.002	<.001	3	2
OV	MCM5 →	-1.391	-0.918	<.001	.002	3	1
OV	GINS1 →	-0.978	-0.964	.001	.001	3	1
OV	NDUFAF5 →	-0.780	-1.151	.006	.002	3	1
OV	H2BW2 →	-0.450	-1.094	.003	.002	3	1
OV	COPE →	-0.643	-0.841	.008	.009	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 889 associations by consensus.

TSHZ2 vs RORA-AS2 — LSCC

Explore this scatter interactively →