Across TCGA cell cohorts, TSEN15 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,193 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TSEN15-associated GO terms across cancer lineages are Nucleotide-excision repair, Regulation of DNA damage checkpoint, and Nuclear division. Each is linked with TSEN15 in more than 10 cancer types. Because this analysis shows association rather than direction, both TSEN15-to-partner and partner-to-TSEN15 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TSEN15→partner) and Y-score (partner→TSEN15) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Nucleotide-excision repair →	+0.081	+0.971	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA damage checkpoint →	+0.068	+0.694	<.001	<.001	3	10
LUNG_SCLC	Nuclear division →	+0.049	+0.664	.002	.002	3	9
LUNG_NSCLC_LUSC	Semaphorin-plexin signaling pathway →	-0.119	-1.012	.003	.002	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of cell cycle checkpoint →	+0.096	+0.899	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of G2/M transition of mitotic cell cycle →	+0.063	+0.695	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,193 associations by consensus.

Exploration

TSEN15 survival (RNA) · tumor vs normal (RNA) · all TSEN15 data types