TRUB1

Across TCGA patient cohorts, TRUB1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,215 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRUB1-associated genes across cancer lineages are ATE1, DCLRE1A, and SMC3. Each is linked with TRUB1 in more than 6 cancer types. Because this analysis shows association rather than direction, both TRUB1-to-partner and partner-to-TRUB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRUB1 versus ATE1 in HNSC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRUB1→partner) and Y-score (partner→TRUB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ATE1 →	+0.745	+0.339	.002	<.001	3	7
LSCC	DCLRE1A →	+0.588	+0.351	<.001	<.001	3	7
HNSC	SMC3 →	+0.688	+0.194	.006	.002	3	6
HNSC	TIAL1 →	+0.609	+0.257	<.001	<.001	3	6
OV	ATP5MD →	+0.736	+0.475	<.001	<.001	3	6
OV	TWNK →	+0.766	+0.320	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,215 associations by consensus.

TRUB1 vs ATE1 — HNSC

Explore this scatter interactively →