TRUB1

Across TCGA pan-cancer cohorts, TRUB1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated TRUB1 data layer compared with 2 for mutation status and 7 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TRUB1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TRUB1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and LGG show a favorable association.

KIRC, UVM, and LGG are the cancer types where TRUB1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Tertile	All	0.699	0.548	.003	47	view →
UVM	DFS	Tertile	III,IV	0.279	0.860	.003	42	view →
LGG	DFS	Median	All	0.474	0.305	<.001	38	view →
SCLC	OS	Quartile	All	0.607	0.850	.017	35	view →
ACC	DFS	Median	II,III,IV	0.160	0.629	<.001	18	view →
LIHC	DFS	Tertile	III,IV	0.174	0.373	.011	17	view →
LUSC	DFS	Tertile	All	0.816	0.559	.004	16	view →
KIRP	DFS	Median	All	0.879	0.940	.015	15	view →
BLCA	DFS	Quartile	All	0.204	0.578	.008	12	view →
DLBC	DFS	Tertile	All	0.688	1.000	.006	12	view →
KICH	DFS	Tertile	All	0.585	1.000	.023	11	view →
COAD	OS	Tertile	All	0.935	0.784	.005	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

TRUB1–KIRC (OS)

Open the KIRC breakdown →