TRUB1

Across TCGA pan-cancer cohorts, TRUB1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of TRUB1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where TRUB1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRUB1 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

BLCA, HNSC, and THCA are the cancer types where TRUB1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRUB1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	All	+0.612	<.001	11	view →
HNSC	All	All	+0.469	<.001	8	view →
THCA	Male	All	−0.459	.002	7	view →
LUAD	Male	All	+0.899	<.001	6	view →
STAD	All	II,III,IV	+0.755	<.001	6	view →
BRCA	All	III,IV	+0.604	<.001	6	view →
KIRC	All	All	−0.272	<.001	6	view →
CHOL	All	All	+1.321	<.001	5	view →
KICH	All	All	−0.700	<.001	5	view →
LUSC	Male	All	+0.689	<.001	5	view →
LIHC	All	All	+0.370	.001	5	view →
ESCA	All	II,III,IV	+1.115	.029	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

TRUB1–BLCA

Open the BLCA breakdown →