TRUB1

Across TCGA cell cohorts, TRUB1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,229 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRUB1-associated GO terms across cancer lineages are Positive regulation of mitochondrial ATP synthesis coupled electron transport, Defense response to bacterium, and Regulation of DNA damage checkpoint. Each is linked with TRUB1 in more than 12 cancer types. Because this analysis shows association rather than direction, both TRUB1-to-partner and partner-to-TRUB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of mitochondrial ATP synthesis coupled electron transport grouped by TRUB1-low versus TRUB1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRUB1→partner) and Y-score (partner→TRUB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.164	+0.800	.006	<.001	3	13
LARGE_INTESTINE	Defense response to bacterium →	-0.101	-0.664	<.001	<.001	3	12
OVARY	Regulation of DNA damage checkpoint →	+0.104	+0.760	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Regulation of mitochondrial ATP synthesis coupled electron transport →	+0.121	+0.678	.002	.002	3	12
STOMACH	Regulation of body fluid levels →	-0.071	-0.691	.002	.005	2	13
BLOOD_Myeloma	Regulation of centriole replication →	+0.079	+0.943	.005	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,229 associations by consensus.

Positive regulation of mitochondrial ATP synthesis coupled electron transport by TRUB1 expression — BLOOD_Myeloma

Explore this box plot interactively →