TRPV4

Across TCGA patient cohorts, TRPV4 protein abundance is significantly associated with the RNA expression of many other genes, with 9,088 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRPV4-associated genes across cancer lineages are FUT6, TTLL10, and ZBTB7C. Each is linked with TRPV4 in more than 3 cancer types. Because this analysis shows association rather than direction, both TRPV4-to-partner and partner-to-TRPV4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRPV4 versus FUT6 in CCRCC, with a Pearson correlation of 0.52.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPV4→partner) and Y-score (partner→TRPV4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	FUT6 →	+1.451	+0.391	<.001	<.001	3	4
UCEC	TTLL10 →	+0.809	+0.460	.006	.007	3	3
LSCC	ZBTB7C →	+1.454	+0.534	<.001	<.001	3	3
UCEC	TTC30B →	+0.638	+0.483	<.001	<.001	3	3
UCEC	RPL4P7 →	-0.593	-0.429	.002	.005	3	3
LUAD	ADGRD1 →	-1.162	-0.588	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,088 associations by consensus.

TRPV4 vs FUT6 — CCRCC

Explore this scatter interactively →