TRPM3

Across TCGA cell cohorts, TRPM3 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,163 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible TRPM3-associated GO terms across cancer lineages are Transcription initiation-coupled chromatin remodeling, Aldehyde catabolic process, and Calcium-dependent cell-cell adhesion. Each is linked with TRPM3 in more than 4 cancer types. Because this analysis shows association rather than direction, both TRPM3-to-partner and partner-to-TRPM3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription initiation-coupled chromatin remodeling grouped by TRPM3-low versus TRPM3-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPM3→partner) and Y-score (partner→TRPM3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Transcription initiation-coupled chromatin remodeling →	+0.059	+0.941	<.001	.004	3	5
CNS	Aldehyde catabolic process →	+0.123	+1.390	<.001	.004	3	4
SKIN	Calcium-dependent cell-cell adhesion →	-0.251	-1.285	<.001	<.001	3	4
SKIN	Negative regulation of TOR signaling →	+0.050	+1.320	<.001	<.001	3	4
SKIN	Epigenetic regulation of gene expression →	+0.030	+0.974	.001	<.001	2	5
BLOOD_Leukemia	Urogenital system development →	-0.091	-0.014	.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,163 associations by consensus.

Transcription initiation-coupled chromatin remodeling by TRPM3 expression — SKIN

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