TRPC4AP

Across TCGA cell cohorts, TRPC4AP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,106 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRPC4AP-associated GO terms across cancer lineages are Mitotic centrosome separation, Golgi vesicle transport, and Vesicle-mediated transport to the plasma membrane. Each is linked with TRPC4AP in more than 17 cancer types. Because this analysis shows association rather than direction, both TRPC4AP-to-partner and partner-to-TRPC4AP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitotic centrosome separation grouped by TRPC4AP-low versus TRPC4AP-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRPC4AP→partner) and Y-score (partner→TRPC4AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Mitotic centrosome separation →	+0.134	+1.198	<.001	<.001	3	18
STOMACH	Golgi vesicle transport →	+0.097	+1.091	<.001	<.001	3	15
BONE	Vesicle-mediated transport to the plasma membrane →	+0.073	+0.446	.001	<.001	2	16
SKIN	Lysosomal transport →	+0.058	+0.634	<.001	.004	3	15
UPPER_AERODIGESTIVE_TRACT	Establishment of protein localization to vacuole →	+0.101	+1.036	<.001	<.001	2	15
SKIN	Endocytic recycling →	+0.070	+0.878	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,106 associations by consensus.

Mitotic centrosome separation by TRPC4AP expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →