TRNAU1AP

Across TCGA patient cohorts, TRNAU1AP mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRNAU1AP-associated genes across cancer lineages are STAT3_pY705, ATM, and Caspase-7-cleavedD198. Each is linked with TRNAU1AP in more than 1 cancer types. Because this analysis shows association rather than direction, both TRNAU1AP-to-partner and partner-to-TRNAU1AP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, STAT3_pY705 grouped by TRNAU1AP-low versus TRNAU1AP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRNAU1AP→partner) and Y-score (partner→TRNAU1AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	STAT3_pY705 →	-0.432	-1.906	<.001	.016	3	2
UCEC	ATM →	-0.688	-3.446	<.001	.005	3	2
UCEC	Caspase-7-cleavedD198 →	+0.515	+2.019	.031	.017	3	2
UCEC	14-3-3_beta →	-0.084	-2.295	.037	.033	3	1
UCEC	eEF2 →	+0.355	+2.321	.013	.033	3	1
UCEC	EGFR_pY1068 →	-0.303	-3.087	.002	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

STAT3_pY705 by TRNAU1AP expression — UCEC

Explore this box plot interactively →