TRNAU1AP

Across TCGA pan-cancer cohorts, TRNAU1AP RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of TRNAU1AP’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where TRNAU1AP RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRNAU1AP is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC, KIRC, and KICH are the cancer types where TRNAU1AP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRNAU1AP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	III,IV	+0.805	<.001	11	view →
KIRC	Male	IV	+0.654	<.001	11	view →
KICH	Female	II,III,IV	−1.868	<.001	10	view →
LIHC	Female	II,III,IV	+1.004	<.001	9	view →
THCA	All	All	+0.202	<.001	6	view →
BLCA	All	III,IV	+0.440	.005	5	view →
COAD	Female	All	+0.378	.002	4	view →
CHOL	Male	All	+1.693	<.001	3	view →
STAD	All	II,III,IV	+0.402	.007	3	view →
LUAD	All	All	+0.232	<.001	3	view →
ESCA	All	All	+0.467	.028	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

TRNAU1AP–HNSC

Open the HNSC breakdown →