TRMU

Across TCGA patient cohorts, TRMU RNA expression is significantly associated with the protein abundance of many other proteins, with 13,815 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRMU-associated proteins across cancer lineages are MCM3, MCM4, and MCM7. Each is linked with TRMU in more than 6 cancer types. Because this analysis shows association rather than direction, both TRMU-to-partner and partner-to-TRMU results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRMU versus MCM3 in GBM, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMU→partner) and Y-score (partner→TRMU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MCM3 →	+0.662	+0.263	<.001	.005	3	7
GBM	MCM4 →	+0.584	+0.272	<.001	.004	3	7
BRCA	MCM7 →	+0.635	+0.580	<.001	<.001	3	7
LSCC	ATXN10 →	+0.373	+0.340	<.001	<.001	3	7
BRCA	SMC2 →	+0.539	+0.494	<.001	.001	3	6
LSCC	MCM5 →	+0.546	+0.397	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,815 associations by consensus.

TRMU vs MCM3 — GBM

Explore this scatter interactively →