TRMT1L

Across TCGA patient cohorts, TRMT1L mutation is significantly associated with the RNA expression of many other genes, with 4,097 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRMT1L-associated genes across cancer lineages are RN7SL248P, VTRNA2-2P, and RNA5SP408. Each is linked with TRMT1L in more than 1 cancer types. Because this analysis shows association rather than direction, both TRMT1L-to-partner and partner-to-TRMT1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by TRMT1L-low versus TRMT1L-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT1L→partner) and Y-score (partner→TRMT1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.057	+3.137	<.001	.005	3	2
CESC	VTRNA2-2P →	+0.412	+4.601	<.001	.004	3	2
LUAD	RNA5SP408 →	+0.308	+7.930	<.001	.008	3	2
UCEC	RN7SL237P →	+0.250	+1.795	<.001	.007	3	2
LUSC	SNORD82 →	+0.553	+4.447	<.001	.006	3	2
LUSC	UBE2V1P12 →	+0.204	+5.578	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,097 associations by consensus.

RN7SL248P by TRMT1L expression — UCEC

Explore this box plot interactively →