TRMT13

Across TCGA patient cohorts, TRMT13 mutation is significantly associated with the RNA expression of many other genes, with 1,499 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRMT13-associated genes across cancer lineages are ICE2P1, RNU6-1228P, and RN7SKP43. Each is linked with TRMT13 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRMT13-to-partner and partner-to-TRMT13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ICE2P1 grouped by TRMT13-low versus TRMT13-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT13→partner) and Y-score (partner→TRMT13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	ICE2P1 →	+0.115	+4.202	<.001	.008	3	2
LGG	RNU6-1228P →	+0.429	+7.646	<.001	<.001	3	2
LUSC	RN7SKP43 →	+0.204	+5.151	.001	.007	3	2
UCEC	ATP6V1G1P4 →	+0.193	+1.562	.004	.006	3	2
UCEC	USP9YP2 →	+0.012	+4.481	<.001	.002	3	2
UCEC	RNU7-29P →	+0.132	+2.783	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,499 associations by consensus.

ICE2P1 by TRMT13 expression — READ

Explore this box plot interactively →