Q-omics provides the consensus-scored RN7SKP43 profile across patient tissues and cancer cell-line models. RN7SKP43 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in THCA. Among the 18 cancer types available for tumor–normal comparison, RN7SKP43 is differentially expressed in 1, with the highest sampling consensus in KIRC. Additionally, RN7SKP43 RNA expression shows 8,988 significant gene co-expression associations, with the highest sampling consensus in SKCM. Together, these results highlight THCA, KIRC, and SKCM as cancer lineages where RN7SKP43 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RN7SKP43 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RN7SKP43 survival associations across molecular data types. RN7SKP43 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RN7SKP43 RNA expression–survival associations across cancer types. High RN7SKP43 expression shows unfavorable associations in THCA, BLCA, LUAD, STAD and PAAD, but favorable associations in ESCA. The THCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify THCA as the clearest survival context for RN7SKP43 RNA expression.
This table summarizes RN7SKP43 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for RN7SKP43. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RN7SKP43 shows higher tumor expression in KIRC. The KIRC box plot shows higher RN7SKP43 RNA expression in tumor versus normal tissue (log2 FC = +0.020, t-test p = .012).
This table shows molecular features associated with RN7SKP43 in patient tissues and cancer cell lines. In patient samples, RN7SKP43 shows the broadest associations at the RNA and protein expression levels, with SKCM recurring as the lineage with the largest associated feature set.