Across TCGA pan-cancer cohorts, RN7SKP43 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of RN7SKP43’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RN7SKP43 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RN7SKP43 is over-expressed in tumor.
KIRC are the cancer types where RN7SKP43 tumor–normal differential expression is most reproducible.