TRMT10C

Across TCGA patient cohorts, TRMT10C protein abundance is significantly associated with the RNA expression of many other genes, with 18,383 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRMT10C-associated genes across cancer lineages are RAB8B, PDE1A, and SYNE1. Each is linked with TRMT10C in more than 7 cancer types. Because this analysis shows association rather than direction, both TRMT10C-to-partner and partner-to-TRMT10C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, TRMT10C versus RAB8B in OV, with a Pearson correlation of -0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT10C→partner) and Y-score (partner→TRMT10C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RAB8B →	-0.656	-0.381	<.001	<.001	3	8
OV	PDE1A →	-1.067	-0.475	.001	<.001	2	8
LSCC	SYNE1 →	-0.825	-0.416	<.001	<.001	3	7
LSCC	CCDC58 →	+0.788	+0.569	<.001	<.001	3	7
BRCA	ZEB2 →	-0.699	-0.286	<.001	<.001	3	7
OV	HIC1 →	-0.724	-0.454	.003	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,383 associations by consensus.

TRMT10C vs RAB8B — OV

Explore this scatter interactively →