TRMT10B

Across TCGA patient cohorts, TRMT10B mutation is significantly associated with the RNA expression of many other genes, with 1,621 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRMT10B-associated genes across cancer lineages are PSAT1P4, RN7SL654P, and CCL5. Each is linked with TRMT10B in more than 1 cancer types. Because this analysis shows association rather than direction, both TRMT10B-to-partner and partner-to-TRMT10B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSAT1P4 grouped by TRMT10B-low versus TRMT10B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRMT10B→partner) and Y-score (partner→TRMT10B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PSAT1P4 →	+0.121	+1.563	.002	.007	3	2
UCEC	RN7SL654P →	+0.087	+2.372	.004	.009	3	2
UCEC	CCL5 →	+1.026	+2.343	.001	<.001	3	1
UCEC	LINC02550 →	-0.430	-3.576	.009	.002	3	1
UCEC	LINC01607 →	-0.751	-3.885	<.001	<.001	3	1
UCEC	LINC02637 →	-0.251	-3.407	.005	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,621 associations by consensus.

PSAT1P4 by TRMT10B expression — UCEC

Explore this box plot interactively →