TRIM77

RNA expression — cross-omics
Cross-omicsRNA → MUTATIONCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, TRIM77 RNA expression is significantly associated with the mutation status of many other genes, with 139 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible TRIM77-associated genes across cancer lineages are AKAP9, PLXND1, and IRF2BPL. Each is linked with TRIM77 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM77-to-partner and partner-to-TRIM77 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM77→partner) and Y-score (partner→TRIM77) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UPPER_AERODIGESTIVE_TRACTAKAP9 →+5.357+0.030.003<.00132
UPPER_AERODIGESTIVE_TRACTPLXND1 →+4.357+0.022.006<.00132
BLOOD_LymphomaIRF2BPL →+4.662+0.022.003<.00132
BLOOD_LymphomaLRP1 →+3.662+0.013.009<.00132
LUNG_NSCLC_LUSCMYH15 →+3.000+0.036.006<.00131
LUNG_NSCLC_LUSCZNF611 →+4.584+0.055.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 139 associations by consensus.

Exploration