Across TCGA pan-cancer cohorts, TRIM77 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of TRIM77’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where TRIM77 RNA is repressed in tumor relative to normal tissue. In most cancer types TRIM77 is over-expressed in tumor, although a few such as LIHC show the opposite, repressed pattern.

LIHC and LUSC are the cancer types where TRIM77 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRIM77 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	All	−0.006	.018	2	view →
LUSC	All	All	+0.012	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: TRIM77 RNA expression & survival · all TRIM77 data types