TRIM72

Across TCGA patient cohorts, TRIM72 mutation is significantly associated with the RNA expression of many other genes, with 180 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM72-associated genes across cancer lineages are RNU7-79P, SNX33P1, and RNU6-380P. Each is linked with TRIM72 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRIM72-to-partner and partner-to-TRIM72 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU7-79P grouped by TRIM72-low versus TRIM72-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM72→partner) and Y-score (partner→TRIM72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU7-79P →	+0.735	+2.833	<.001	.006	3	3
BRCA	SNX33P1 →	+0.042	+5.045	<.001	.009	3	2
UCEC	RNU6-380P →	+0.257	+4.470	<.001	.004	3	2
UCEC	RNU7-125P →	+0.793	+3.690	<.001	<.001	3	2
UCEC	RPS23P5 →	+0.181	+3.014	<.001	.004	3	2
COAD	SSX2 →	+0.078	+4.547	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 180 associations by consensus.

RNU7-79P by TRIM72 expression — UCEC

Explore this box plot interactively →