TRIM72

Across TCGA pan-cancer cohorts, TRIM72 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated TRIM72 data layer compared with 4 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TRIM72 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TRIM72 expression acts as an unfavorable survival marker, although some lineages such as SCLC and CESC show a favorable association.

KIRC, SCLC, and LIHC are the cancer types where TRIM72 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.517	0.723	<.001	154	view →
SCLC	DFS	Median	All	0.703	0.277	<.001	137	view →
LIHC	OS	Median	All	0.568	0.798	<.001	62	view →
ACC	DFS	Median	All	0.266	0.761	<.001	46	view →
KIRP	OS	Median	All	0.518	0.819	<.001	27	view →
THCA	DFS	Quartile	III,IV	0.829	0.960	.002	21	view →
LUAD	OS	Tertile	All	0.782	0.887	.016	18	view →
CESC	OS	Quartile	II,III,IV	0.885	0.466	.015	14	view →
SKCM	OS	Quartile	IV	1.000	0.139	.017	10	view →
KICH	OS	Tertile	III,IV	0.178	0.836	.004	10	view →
DLBC	OS	Quartile	All	0.498	1.000	.038	10	view →
LGG	OS	Tertile	All	0.931	0.853	.002	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

TRIM72–KIRC (OS)

Open the KIRC breakdown →