TRIM72

Across TCGA cell cohorts, TRIM72 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,163 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible TRIM72-associated GO terms across cancer lineages are Formation of cytoplasmic translation initiation complex, Viral translational termination-reinitiation, and Positive regulation of telomerase RNA localization to Cajal body. Each is linked with TRIM72 in more than 7 cancer types. Because this analysis shows association rather than direction, both TRIM72-to-partner and partner-to-TRIM72 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Formation of cytoplasmic translation initiation complex grouped by TRIM72-low versus TRIM72-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM72→partner) and Y-score (partner→TRIM72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Formation of cytoplasmic translation initiation complex →	+0.095	+0.041	<.001	.006	3	7
OESOPHAGUS	Viral translational termination-reinitiation →	+0.057	+0.034	.004	.003	2	8
PANCREAS	Positive regulation of telomerase RNA localization to Cajal body →	+0.069	+0.027	.007	.004	3	6
OVARY	Nuclear-transcribed mRNA catabolic process →	+0.047	+0.030	<.001	.001	3	6
BLOOD_Lymphoma	Nucleic acid catabolic process →	+0.029	+0.532	.001	.007	3	6
CNS	RNA catabolic process →	+0.039	+0.079	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,163 associations by consensus.

Formation of cytoplasmic translation initiation complex by TRIM72 expression — PANCREAS

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