TRIM72

Across TCGA cell cohorts, TRIM72 mutation is significantly associated with the RNA expression of many other genes, with 136 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRIM72-associated genes across cancer lineages are SNU13, USP14, and SEMA3G. Each is linked with TRIM72 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM72-to-partner and partner-to-TRIM72 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNU13 grouped by TRIM72-low versus TRIM72-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM72→partner) and Y-score (partner→TRIM72) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SNU13 →	+0.527	+3.212	.001	.006	3	1
LARGE_INTESTINE	USP14 →	+0.706	+3.237	.002	.003	3	1
LARGE_INTESTINE	SEMA3G →	+0.791	+3.212	.003	.006	3	1
LARGE_INTESTINE	C1QBP →	+0.809	+3.299	<.001	.004	3	1
LARGE_INTESTINE	WRAP73 →	+0.575	+3.212	.003	.006	3	1
LARGE_INTESTINE	TCTN3 →	+0.575	+3.212	.005	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 136 associations by consensus.

SNU13 by TRIM72 expression — LARGE_INTESTINE

Explore this box plot interactively →