TRIM7

Across TCGA patient cohorts, TRIM7 mutation is significantly associated with the RNA expression of many other genes, with 1,123 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM7-associated genes across cancer lineages are TRDJ2, RN7SKP43, and BNIP3P2. Each is linked with TRIM7 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM7-to-partner and partner-to-TRIM7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRDJ2 grouped by TRIM7-low versus TRIM7-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM7→partner) and Y-score (partner→TRIM7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRDJ2 →	+0.637	+3.214	.008	.005	3	2
COAD	RN7SKP43 →	+0.196	+5.412	<.001	.001	3	2
CESC	BNIP3P2 →	+0.054	+5.252	<.001	.002	3	2
UCEC	RN7SL248P →	+0.049	+2.915	<.001	.007	3	2
UCEC	RN7SKP286 →	+0.051	+4.253	<.001	<.001	3	2
UCEC	LINC02829 →	+0.086	+1.654	.007	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,123 associations by consensus.

TRDJ2 by TRIM7 expression — COAD

Explore this box plot interactively →