TRIM69

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, TRIM69 mutation is significantly associated with the RNA expression of many other genes, with 1,793 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM69-associated genes across cancer lineages are RNA5SP20, TRAJ25, and LINC02585. Each is linked with TRIM69 in more than 2 cancer types. Because this analysis shows association rather than direction, both TRIM69-to-partner and partner-to-TRIM69 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM69→partner) and Y-score (partner→TRIM69) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRNA5SP20 →+0.658+3.542.001.00533
UCECTRAJ25 →+0.340+2.464<.001.00733
UCECLINC02585 →+0.496+3.632.006.00133
UCECSNRPGP17 →+0.259+1.741<.001.00532
UCECSNORD115-40 →+0.232+4.230<.001.00432
UCECRNVU1-29 →+0.535+1.772<.001.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,793 associations by consensus.

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