TRIM62

Across TCGA patient cohorts, TRIM62 mutation is significantly associated with the RNA expression of many other genes, with 596 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM62-associated genes across cancer lineages are SLC29A4P2, C1QBPP1, and KRTAP3-4P. Each is linked with TRIM62 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM62-to-partner and partner-to-TRIM62 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC29A4P2 grouped by TRIM62-low versus TRIM62-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM62→partner) and Y-score (partner→TRIM62) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	SLC29A4P2 →	+0.024	+5.033	<.001	.003	3	2
BLCA	C1QBPP1 →	+0.032	+4.433	.002	.007	3	2
BLCA	KRTAP3-4P →	+0.163	+4.704	<.001	.005	3	2
BLCA	RPS3AP1 →	+0.077	+4.433	<.001	.007	3	2
BLCA	UBTFL2 →	+0.065	+4.996	<.001	<.001	3	2
HNSC	RN7SKP169 →	+0.158	+5.182	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 596 associations by consensus.

SLC29A4P2 by TRIM62 expression — BLCA

Explore this box plot interactively →