TRIM62

Across TCGA pan-cancer cohorts, TRIM62 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated TRIM62 data layer compared with 4 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in small cell lung cancer (SCLC), where higher TRIM62 RNA is associated with better overall survival. In most high-consensus cancer types, elevated TRIM62 expression acts as an unfavorable survival marker, although some lineages such as SCLC and BLCA show a favorable association.

SCLC, ACC, and BLCA are the cancer types where TRIM62 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SCLC	OS	Median	All	0.529	0.183	<.001	104	view →
ACC	DFS	Median	All	0.250	0.628	<.001	73	view →
BLCA	OS	Median	All	0.527	0.370	.005	56	view →
LIHC	DFS	Quartile	All	0.308	0.504	<.001	47	view →
LUAD	OS	Quartile	All	0.439	0.267	.001	39	view →
KICH	DFS	Quartile	II,III,IV	0.540	1.000	.002	34	view →
GBM	DFS	Median	All	0.333	0.182	<.001	31	view →
HNSC	DFS	Median	All	0.764	0.651	.006	25	view →
COAD	DFS	Tertile	All	0.412	0.803	.006	22	view →
UCEC	DFS	Quartile	All	0.777	0.884	.005	16	view →
ESCA	DFS	Tertile	II,III,IV	1.000	0.394	.031	12	view →
THYM	DFS	Median	II,III,IV	0.946	0.519	.006	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

TRIM62–SCLC (OS)

Open the SCLC breakdown →