TRIM60

Across TCGA cell cohorts, TRIM60 RNA expression is significantly associated with the mutation status of many other genes, with 94 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible TRIM60-associated genes across cancer lineages are TASOR2, IRF4, and ADD2. Each is linked with TRIM60 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM60-to-partner and partner-to-TRIM60 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TASOR2 grouped by TRIM60-low versus TRIM60-high in SOFT_TISSUE.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM60→partner) and Y-score (partner→TRIM60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	TASOR2 →	+4.930	+0.375	.008	<.001	3	2
SOFT_TISSUE	IRF4 →	+4.930	+0.375	.008	<.001	3	2
SOFT_TISSUE	ADD2 →	+5.515	+0.283	<.001	<.001	3	2
BLOOD_Leukemia	ADAMTS1 →	+3.786	+0.018	.002	<.001	3	2
LUNG_NSCLC_LUAD	IL1RL2 →	+3.228	+0.013	.003	<.001	3	2
BLOOD_Leukemia	MAP3K2 →	+3.464	+0.016	.003	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 94 associations by consensus.

TASOR2 by TRIM60 expression — SOFT_TISSUE

Explore this box plot interactively →