Across TCGA pan-cancer cohorts, TRIM60 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of TRIM60’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where TRIM60 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types TRIM60 is over-expressed in tumor.
KIRP are the cancer types where TRIM60 tumor–normal differential expression is most reproducible.