TRIM60

Across TCGA pan-cancer cohorts, TRIM60 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated TRIM60 data layer compared with 7 for mutation status.

The strongest signal is observed in kidney chromophobe (KICH), where higher TRIM60 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated TRIM60 expression acts as an unfavorable survival marker.

KICH, BLCA, and READ are the cancer types where TRIM60 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.369	0.922	<.001	108	view →
BLCA	OS	Tertile	All	0.196	0.697	<.001	105	view →
READ	OS	Tertile	All	0.166	0.830	<.001	90	view →
BRCA	OS	Tertile	IV	0.106	0.791	<.001	81	view →
LIHC	DFS	Tertile	All	0.368	0.582	.001	45	view →
MESO	OS	Tertile	II,III,IV	0.246	0.582	.012	36	view →
COAD	DFS	Tertile	III,IV	0.165	0.703	<.001	36	view →
KIRC	OS	Tertile	All	0.517	0.652	.012	33	view →
DLBC	OS	Tertile	III,IV	0.175	0.874	.025	27	view →
SCLC	OS	Tertile	All	0.219	0.706	.011	18	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	9	view →
STAD	DFS	Tertile	IV	0.087	0.415	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

TRIM60–KICH (DFS)

Open the KICH breakdown →