Across TCGA patient cohorts, TRIM53AP mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRIM53AP-associated genes across cancer lineages are LINC02676, RPSAP24, and TRIM67-AS1. Each is linked with TRIM53AP in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM53AP-to-partner and partner-to-TRIM53AP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM53AP→partner) and Y-score (partner→TRIM53AP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	LINC02676 →	+0.104	+4.495	<.001	.007	3	1
SKCM	RPSAP24 →	+0.064	+4.265	.008	.003	3	1
SKCM	TRIM67-AS1 →	+0.156	+3.878	<.001	.008	3	1
SKCM	RN7SL310P →	+0.090	+4.495	<.001	.007	3	1
SKCM	H2BC2P →	+0.085	+4.884	<.001	.004	3	1
SKCM	IFNA2 →	+0.027	+4.385	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

TRIM53AP survival (RNA) · tumor vs normal (RNA) · all TRIM53AP data types