Q-omics provides the consensus-scored TRIM53AP profile across patient tissues and cancer cell-line models. TRIM53AP expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in BLCA. Additionally, TRIM53AP RNA expression shows 8,264 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight BLCA, and TGCT as cancer lineages where TRIM53AP shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for TRIM53AP — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes TRIM53AP survival associations across molecular data types. TRIM53AP RNA expression shows survival associations in the most cancer types (12), followed by mutation status (3). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible TRIM53AP RNA expression–survival associations across cancer types. High TRIM53AP expression shows unfavorable associations in BLCA, UCEC, MESO, KIRC, CESC and UVM. The BLCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .005). Together, the overview and detailed table identify BLCA as the clearest survival context for TRIM53AP RNA expression.
This table shows molecular features associated with TRIM53AP in patient tissues and cancer cell lines. In patient samples, TRIM53AP shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set. In cancer cell lines, TRIM53AP RNA and mutation anchors are most strongly linked to RNA-expression features, especially in BLOOD_Leukemia.
