Across TCGA patient cohorts, TRIM49C mutation is significantly associated with the RNA expression of many other genes, with 1,538 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible TRIM49C-associated genes across cancer lineages are C11orf98, LINC00294, and RPL23AP7. Each is linked with TRIM49C in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM49C-to-partner and partner-to-TRIM49C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM49C→partner) and Y-score (partner→TRIM49C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	C11orf98 →	+0.529	+3.488	<.001	.002	3	2
SKCM	LINC00294 →	+0.477	+2.328	.006	.003	3	2
SKCM	RPL23AP7 →	+0.605	+3.411	<.001	.004	3	2
UCEC	BUB3 →	+0.489	+3.397	.003	.004	3	2
UCEC	PCGF6 →	+0.538	+2.839	.006	.001	3	2
UCEC	SASS6 →	+0.625	+3.906	.004	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,538 associations by consensus.

Exploration

TRIM49C survival (RNA) · tumor vs normal (RNA) · all TRIM49C data types