TRIM44

Across TCGA patient cohorts, TRIM44 mutation is significantly associated with the RNA expression of many other genes, with 325 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible TRIM44-associated genes across cancer lineages are ATP5MFP1, CDC6, and CBARP. Each is linked with TRIM44 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM44-to-partner and partner-to-TRIM44 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATP5MFP1 grouped by TRIM44-low versus TRIM44-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM44→partner) and Y-score (partner→TRIM44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	ATP5MFP1 →	+0.182	+5.544	<.001	.004	3	2
UCEC	CDC6 →	+0.744	+2.828	.002	.001	3	2
UCEC	CBARP →	+0.711	+2.807	.001	.003	3	2
LUAD	RNU6-89P →	+0.498	+6.315	.001	.001	3	2
UCEC	NF2 →	+0.543	+2.818	.001	.001	3	2
UCEC	C15orf61 →	+0.397	+3.201	.005	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 325 associations by consensus.

ATP5MFP1 by TRIM44 expression — LIHC

Explore this box plot interactively →