TRIM43

Across TCGA patient cohorts, TRIM43 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,589 significant associations in total. THYM shows the largest number of these associations.

The most reproducible TRIM43-associated GO terms across cancer lineages are Regulation of mitochondrial membrane potential, Negative regulation of chromosome organization, and Ribose phosphate biosynthetic process. Each is linked with TRIM43 in more than 9 cancer types. Because this analysis shows association rather than direction, both TRIM43-to-partner and partner-to-TRIM43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitochondrial membrane potential grouped by TRIM43-low versus TRIM43-high in THYM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM43→partner) and Y-score (partner→TRIM43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	Regulation of mitochondrial membrane potential →	+0.046	+0.794	<.001	<.001	3	10
UCEC	Negative regulation of chromosome organization →	+0.029	+0.258	<.001	<.001	3	9
STAD	Ribose phosphate biosynthetic process →	+0.049	+0.075	<.001	.007	2	10
STAD	Mitochondrial translation →	+0.058	+0.112	<.001	.003	2	10
THYM	RNA localization →	+0.031	+0.602	.002	.002	2	9
THYM	RNA decapping →	+0.036	+0.718	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,589 associations by consensus.

Regulation of mitochondrial membrane potential by TRIM43 expression — THYM

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