TRIM36-IT1

Across TCGA patient cohorts, TRIM36-IT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,744 significant associations in total. STAD shows the largest number of these associations.

The most reproducible TRIM36-IT1-associated GO terms across cancer lineages are Positive regulation of DNA repair, Positive regulation of DNA metabolic process, and Protein-RNA complex organization. Each is linked with TRIM36-IT1 in more than 17 cancer types. Because this analysis shows association rather than direction, both TRIM36-IT1-to-partner and partner-to-TRIM36-IT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA repair grouped by TRIM36-IT1-low versus TRIM36-IT1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM36-IT1→partner) and Y-score (partner→TRIM36-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Positive regulation of DNA repair →	+0.054	+0.254	<.001	<.001	3	18
STAD	Positive regulation of DNA metabolic process →	+0.049	+0.232	<.001	<.001	3	17
ESCA	Protein-RNA complex organization →	+0.061	+0.232	<.001	<.001	3	16
STAD	Positive regulation of plasma membrane bounded cell projection assembly →	+0.042	+0.197	<.001	<.001	3	16
STAD	Protein folding →	+0.052	+0.226	<.001	<.001	3	16
ESCA	Peptidyl-lysine methylation →	+0.045	+0.250	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,744 associations by consensus.

Positive regulation of DNA repair by TRIM36-IT1 expression — ESCA

Explore this box plot interactively →