TRIM36-IT1

Across TCGA pan-cancer cohorts, TRIM36-IT1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of TRIM36-IT1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where TRIM36-IT1 RNA is repressed in tumor relative to normal tissue. In most cancer types TRIM36-IT1 is over-expressed in tumor, although a few such as COAD and LUSC show the opposite, repressed pattern.

COAD, LUSC, and PRAD are the cancer types where TRIM36-IT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in TRIM36-IT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	All	−0.104	<.001	7	view →
LUSC	All	All	−0.039	.001	4	view →
PRAD	All	All	+0.129	.002	2	view →
KIRC	Male	All	+0.013	.017	2	view →
KICH	All	All	−0.024	.026	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

TRIM36-IT1–COAD

Open the COAD breakdown →