TRIM36-IT1

Across TCGA pan-cancer cohorts, TRIM36-IT1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated TRIM36-IT1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher TRIM36-IT1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated TRIM36-IT1 expression acts as an unfavorable survival marker, although some lineages such as STAD and LUAD show a favorable association.

KIRC, LUSC, and UCEC are the cancer types where TRIM36-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.513	0.685	<.001	155	view →
LUSC	OS	Tertile	II,III,IV	0.374	0.653	<.001	117	view →
UCEC	OS	Tertile	All	0.803	0.903	<.001	98	view →
STAD	DFS	Quartile	All	0.518	0.203	.006	72	view →
CESC	OS	Quartile	IV	0.141	0.659	<.001	32	view →
LUAD	OS	Tertile	All	0.607	0.296	.018	30	view →
LIHC	DFS	Tertile	All	0.190	0.535	.025	27	view →
ACC	DFS	Tertile	IV	0.012	0.310	.002	24	view →
ESCA	DFS	Median	II,III,IV	0.410	0.880	.021	18	view →
CHOL	OS	Tertile	III,IV	0.275	0.886	.045	18	view →
BLCA	OS	Tertile	III,IV	0.547	0.335	.032	15	view →
LAML	DFS	Median	All	0.589	0.324	.010	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

TRIM36-IT1–KIRC (OS)

Open the KIRC breakdown →