TRIM32

Across TCGA cell cohorts, TRIM32 mutation is significantly associated with the RNA expression of many other genes, with 212 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible TRIM32-associated genes across cancer lineages are OR7G3, SCYGR4, and NPBWR2. Each is linked with TRIM32 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM32-to-partner and partner-to-TRIM32 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7G3 grouped by TRIM32-low versus TRIM32-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM32→partner) and Y-score (partner→TRIM32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR7G3 →	+0.043	+6.266	<.001	<.001	3	2
OESOPHAGUS	SCYGR4 →	+0.011	+4.017	<.001	.007	3	1
OVARY	NPBWR2 →	+0.047	+4.029	.004	.009	3	1
OVARY	ADGRE3 →	+0.011	+4.450	<.001	.004	3	1
OVARY	DCD →	+0.158	+4.990	<.001	.001	3	1
OVARY	C14orf180 →	+0.045	+4.228	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 212 associations by consensus.

OR7G3 by TRIM32 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →