TRIM16L

Across TCGA cell cohorts, TRIM16L mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible TRIM16L-associated genes across cancer lineages are OC90 and TLE7. Each is linked with TRIM16L in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM16L-to-partner and partner-to-TRIM16L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OC90 grouped by TRIM16L-low versus TRIM16L-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM16L→partner) and Y-score (partner→TRIM16L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OC90 →	+0.013	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TLE7 →	+0.022	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OC90 by TRIM16L expression — BLOOD_Leukemia

Explore this box plot interactively →