Across TCGA patient cohorts, TRIM16 protein abundance is significantly associated with the RNA expression of many other genes, with 2,221 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible TRIM16-associated genes across cancer lineages are GALNT14, KLK12, and MIR1270. Each is linked with TRIM16 in more than 1 cancer types. Because this analysis shows association rather than direction, both TRIM16-to-partner and partner-to-TRIM16 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (TRIM16→partner) and Y-score (partner→TRIM16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	GALNT14 →	+2.170	+0.688	.007	.007	3	2
LUAD	KLK12 →	+3.438	+0.656	<.001	<.001	3	2
LUAD	MIR1270 →	-1.691	-0.594	.003	.001	3	2
LSCC	CDK6 →	+1.038	+0.622	<.001	.002	3	2
BRCA	TMPRSS4 →	+1.525	+0.717	.003	<.001	3	2
BRCA	SCUBE1 →	-1.115	-0.743	.002	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,221 associations by consensus.

Exploration

TRIM16 survival (RNA) · tumor vs normal (RNA) · all TRIM16 data types